Table 3.
Multivariate Cox regression analysis of prognostic factors affecting survival
| Variable | Category | Multivariate analysis HR (95% CI) | P value |
|---|---|---|---|
| T-stage | Early | Reference | <0.001 |
| Advanced | 0.08 (0.02–0.30) | ||
| Concurrent diseases | Absent | Reference | 0.003 |
| Present | 3.72 (1.58–8.76) | ||
| Total dose | ⩾135 Gy | Reference | 0.10 |
| <135 Gy | 2.43 (0.83–7.14) | ||
| Response | CR | Reference | <0.001 |
| PR | 4.76 (2.14–10.59) | ||
| PD | 8.66 (2.19–34.29) | ||
| Protocol | Fractionated | Reference | 0.53 |
| Single-dose | 0.70 (0.22–2.19) |
T-stage = stage of cutaneous squamous cell carcinoma; HR = hazard ratio; CI = confidence interval; CR = complete response; PR = partial response; PD = progressive disease