Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 18;13(2):185. doi: 10.3390/cells13020185

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Localization of SREBP2 in response to MBTP1 inhibition in native CFBE41o-cells. The localization of SREBP2 was assessed using Western blot in cytosolic extract (lane 1), nuclei enriched samples (lanes 2 to 4), and total lysate lane (6). To ensure the enrichment of nuclear proteins, aldolase was used as a cytosolic marker (upper panel) and Histone H1 as a nuclear marker (middle panel). SREBP2’s cleaved form (lower panel) was absent in nuclear extract of treated cells indicating that its cleavage was abolished.