Table 2.
Univariate and multivariate Cox analysis results for the OS of MTC patients.
| Variable | Univariate Survival Analysis | Multivariate Survival Analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-Value | HR | 95% CI | p-Value | |
| Age (Years) | ||||||
| <40 | Reference | Reference | ||||
| 40–59 | 2.558 | 1.540–4.250 | <0.001 | 2.920 | 1.750–4.872 | <0.001 |
| ≥60 | 7.354 | 4.543–11.905 | <0.001 | 7.610 | 4.674–12.392 | <0.001 |
| Sex | ||||||
| Female | Reference | Reference | ||||
| Male | 1.743 | 1.398–2.172 | <0.001 | 1.011 | 0.797–1.283 | 0.928 |
| Race | ||||||
| White | Reference | |||||
| Black | 0.904 | 0.613–1.334 | 0.611 | - | - | - |
| Asian or Pacific Islander | 0.405 | 0.201–0.818 | 0.012 | - | - | - |
| American Indian/Alaska Native | 2.160 | 0.537–8.686 | 0.278 | - | - | - |
| Tumor Size | ||||||
| ≤20 | Reference | Reference | ||||
| 20–40 | 1.651 | 1.253–2.174 | <0.001 | 2.338 | 1.219–4.483 | 0.011 |
| ≥40 | 3.386 | 2.605–4.401 | <0.001 | 3.330 | 1.826–6.073 | <0.001 |
| Stage | ||||||
| I | Reference | |||||
| II | 1.299 | 0.900–1.873 | 0.162 | - | - | - |
| III | 1.275 | 0.794–2.048 | 0.314 | - | - | - |
| IV | 4.241 | 3.201–5.620 | <0.001 | - | - | - |
| T Stage | ||||||
| T1 | Reference | |||||
| T2 | 1.299 | 0.942–1.792 | 0.110 | - | - | - |
| T3 | 2.508 | 1.889–3.328 | <0.001 | - | - | - |
| T4 | 5.136 | 3.753–7.030 | <0.001 | - | - | - |
| N Stage | ||||||
| N0 | Reference | Reference | ||||
| N1a | 1.612 | 1.136–2.287 | 0.007 | 1.327 | 0.981–1.793 | 0.066 |
| N1b | 3.007 | 2.373–3.809 | <0.001 | 1.874 | 1.493–2.351 | <0.001 |
| M Stage | ||||||
| M0 | Reference | Reference | ||||
| M1 | 8.317 | 6.364–10.870 | <0.001 | 3.868 | 2.805–5.335 | <0.001 |