FIG. 6.

Effect of C. albicans CAT1 deletion on susceptibility to damage by PMNs. Hyphae of both the parent strain, SC5314 (•), and the homozygous mutant strain, CADW3 (▵), were incubated at 37°C for 60 min with PMNs. Percentages of metabolically active hyphae were determined by measuring the absorbance of supernatants at 450 nm after reduction of XTT, as described in Materials and Methods.