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. 2024 Jan 11;25(2):919. doi: 10.3390/ijms25020919

Figure 3.

Figure 3

Subtypes of TCGA-LIHC cohort and association with previous HCC subtypes and signatures. Integrated analysis of CTNNB1 and TP53 mutations (bottom), DEGs expression data (middle), and molecular subtypes of HCC (top). (Tumor samples, n = 368): C1 (n = 51), C2a (n =64), C2b (n =126), and C3 (n = 127). Metastasis risk subtype, MH for high risk and ML for low risk; RS65, 65-gene risk score; Hippo, Hippo pathway subtype; AH for active Hippo; SOH for silence of Hippo; CCL, cholangiocarcinoma-like subtype; CLHCC for cholangiocarcinoma-like HCC. p-values were calculated using a chi-square test.