TABLE 5.
Analysis of anti-NTHI 12 whole-cell antibody responses in chinchilla immune sera by whole-cell ELISA
| Group | Animals | Anti-NTHI 12 antibody response in serum
|
|||
|---|---|---|---|---|---|
| Mean titer
|
Median titer
|
||||
| IgG response | IgA response | IgG response | IgA response | ||
| 1 | Convalescent from strain 12 infection | 970a | 13a | 670b | 14b |
| 2 | Immunized with strain 12 whole cells | 15,000a | 90a | 10,390b | 81b |
| 3 | Immunized with strain LCDC2 whole cells | 9,970a | 53a | 6,890b | 44b |
| 4 | Control | 60 | 1.6 | 40 | 1.3 |
a
Statistical significance compared to control animals (P < 0.05) in Student’s unpaired t test.
b
Statistical significance compared to control animals (P < 0.05) in the Mann-Whitney rank sum test.