Figure 3.

Increased nitrosative stress in serum of PPMS patients compared to Soma patients. (A–C) Violin plots with overlaying box plots comparing two groups. Boxes display the median as well as the 25th and 75th percentiles. The whiskers extend from the hinge to the largest and smallest values, respectively, but no further than 1.5 * IQR from the hinge. (D) Simple linear regression using age as independent and NOx serum as dependent variable. The area in-between the dotted lines shows the 95% confidence band. IQR—Interquartile range, NOx—Nitrosative stress molecules, ns—Not significant, PPMS—Primary progressive Multiple Sclerosis, Q—CSF/serum ratio, RRMS—Relapsing–remitting Multiple Sclerosis, Soma—Somatic symptom disorder, *—multiplied by.