FIG. 3.

Transfer of immunologic memory for GBSIII PS. BALB/c mice were immunized twice 3 weeks apart with GBSIII-TT conjugate vaccine, and 4 weeks after the second immunization, 2 × 10⁸ spleen cells were adoptively transferred into six naive recipients. All recipient mice were immunized 24 h later with saline (first immunization) and 28 days later with GBSIII-TT (second immunization), and the antibody response to GBSIII PS was measured in serum taken 0, 7, 14, and 28 days after these two immunizations. (A) GBSIII-specific IgG response; (B) GBSIII-specific IgM response. Lines represent the median levels, and error bars indicate the range.