TABLE 1.

Antibody response elicited by various doses of GBSIII-TT conjugate vaccine in BALB/c mice^a

Amt of GBSIII-TT (μg)	Median level of GBSIII IgG antibodies (range) (ng/ml)b afterc:
	Injection 1	Injection 2	Injection 3
0.031	90 (50–100)*	70 (50–90)*	70 (50–100)*
0.125	90 (50–160)*	160 (50–570)*	780 (80–2,260)*
0.5	100 (50–170)*	360 (130–710)*	2,180 (440–13,440)*
2	340 (90–1,220)**	3,710 (1,740–21,940)**	16,080 (5,380–188,700)**
8	690 (310–2,460)***	5,100 (1,180–24,710)***	14,240 (1,770–107,700)***

^aMice were injected i.p. with various doses of GBSIII-TT as described in Materials and Methods. 

^b** and *** versus *, P < 0.05; ** versus ***, the differences in anti-GBSIII IgG levels were not statistically significant (Mann-Whitney test). 

^cMice were bled 21 days after first injection and 24 days after the second and third injections.