Figure 3.

Next-generation sequencing in hiPSCs and hiPSC-CMs. (A) Mutations identified by WES. (B) Mutations identified by targeted sequencing. Genomic alterations are annotated according to the color panel on the right of the image. Missense mutation (brown), nonsense mutation (sky blue), in-frame insertion mutation (green), splice site mutation (gray), and frame-shift mutation (yellow). The time frame for the analysis of samples is shown at the top of the image from early batch (red) and intermediate batch (blue), and the gene names of each identified mutation are listed on the left side of the image.