Figure 1.

Increased plasma OPN levels were associated with long COVID symptoms in patients previously hospitalized for COVID-19. OPN levels from 181 plasma samples obtained during follow-up visits from 122 previously hospitalized COVID-19 patients were compared in the absence and presence of any symptom at any visit, n = 74 vs. n = 107 (A); any symptom at visits occurred 90 days or more (late visits) post-symptom onset, n = 67 vs. n = 87 (B); dyspnea at any visit, n = 102 vs.n = 79, (C); and dyspnea at late visits, n = 91 vs. n = 63 (D). Data are presented as 5–95 whisker plots with median; * p < 0.05, ** p < 0.01. OPN: osteopontin.