Table 2.

Rituximab dosing and relapse frequency.

	Total	AQP4+	MOG+	Double- Seronegative
Induction dose rituximab, range, mg	250–2000	250–2000	500–1000	500–1000
Maintenance dose rituximab, range, mg	100–1000	100–1000	500–1000	500–1000
Cumulative dose rituximab, mean (median), mg	4640 (4100)	4946 (4650)	3281 (3625)	4990 (3850)
Withdrawal of rituximab, n (%)	16 (38%)	7 (29%)	5 (63%)	4 (40%)
Follow-up time, mean (min–max) years *	4.0 (0.5–8.3)	4.4 (0.9–7.7)	2.6 (0.5–4.8)	4.2 (0.8–8.3)
Patients (n) with a relapse during rituximab treatment	21 (50%)	9 (37.5%)	6 (75%)	6 (60%)
Annual relapse rate; mean (median)	0.55 (0.5)	0.21 (0)	1.70 (1.6)	0.48 (0.3)

* From first rituximab dose to sixth months after the last dose.