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. 2024 Jan 21;25(2):1318. doi: 10.3390/ijms25021318

Table 1.

Clinical presentations by different immunohistochemical scores in HER2-negativebreast cancer.

HER2-0
(n = 246)
HER2-Low
(n = 369)
p Value *
Age (years) 0.742
<55 120 (48.7%) 175 (47.4%)
≥55 126 (51.2%) 194 (52.5%)
Tumor size 0.878
T1 (≤2cm) 87 (35.3%) 146 (39.5%)
T2 (2.1–5 cm) 126(51.2%) 166 (44.9%)
T3 (>5 cm) 20 (8.1%) 24(6.5%)
T4 12 (4.8%) 33(8.9%)
NA 1 (0.4%) 0 (0%)
Node 0.182
N0 131 (53.2%) 196 (53.1%)
N1 74 (30.1%) 90 (24.4%)
N2 25 (10.2%) 42 (11.4%)
N3 14 (5.7%) 39 (10.6%)
NA 2 (0.8%) 2 (0.5%)
Stage 0.020 *
I 68 (27.7%) 116 (31.4%)
II 121 (49.2%) 137 (37.1%)
III 35 (14.2%) 77 (20.9%)
IV 22 (8.9%) 39 (10.6%)

HER2-0, HER2 immunohistochemistry score = 0; HER2-low was defined as HER2 immunohistochemistry score (+/++ with FISH (-); * p value via Chi-Square or Fisher’s exact test.