Table 2.

Top pathways represented by the differentially expressed genes in arthritic versus control populations. MetaCore by Thompson Reuters identified the likelihood that 2442 of the 2842 differentially expressed genes identified in the expression profile are involved in these pathways. The other 400 genes could not be assigned to a pathway by the software. The smaller the P-value, the greater the likelihood that the genes are involved in that pathway and the less likely the genes were differentially expressed by chance alone

Pathway name	GeneGo p-value
Antigen presentation by MHC class I and II	1.2e-08
T-cell receptor signaling	2.5e-08
Oxidative phosphorylation	2.2e-08

MHC = major histocompatibility complex