Figure 3.

Enriched gene expression signature changes define region-specific astrocytes transcriptome during postnatal brain development. (A) Overview of the approach for investigating region-specific postnatal astrocyte transcriptome from different brain regions [22]. (B) Principal component analysis plot displaying RNA-Seq results of astrocytes from four brain regions across time points. (C,E,G), Heat maps showing DEGs of each time point. (D,F,H) Number of region-specific or globally conserved DEGs across the time points. DEGs of each time point are listed in Table S3. (I) Heat map and gene lists showing globally conserved genes across the time points. (J–L) Top 5 biological GO terms of DEGs from four brain regions across the time points.