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. 2024 Jan 13;25(2):1021. doi: 10.3390/ijms25021021

Figure 5.

Figure 5

Identification of unique signature genes enriched in brain tumors of cerebellar origin (A) Schematics showing the types of brain tumors that were analyzed in this study. (B) Graph showing the number of genes from comparison analysis of up- or downregulated DEGs from each time point. (C) Top 10 biological GO terms from five types of brain tumors of cerebellar origin. (D) Top 5 KEGG terms of five brain tumor types. (E) Venn diagram displaying the shared or unique gene number from each tumor type. (F) Gene list of cerebellar brain tumor shared genes and heat map showing the expression pattern. (G) Heat maps of cerebellar brain tumor shared genes across the time points. (H) Venn diagram showing the number of genes that were specifically upregulated in the cerebellum at P7. (I) Heat map and gene list of cerebellar-specific P7 upregulated genes. (J) Dynamic Kif11 expression change in astrocytes between P7 and P14 (n = 4 per each group, **** p < 0.0001). Data are shown as the mean ± SEM.