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(A) Interactions in the active site of OGG1 bound to 8-oxoG (PDB ID: 1EBM) [123]. (B) The proposed model of 8-oxoA binding based on the OGG1:8-oxoG structure (PDB ID: 1EBM). Hydrogen bonds between nucleobases and interactions with the enzyme amino acids are represented with dashed lines; water molecules are indicated as red spheres. The Q315 and G42 O atoms are shown in red and N in blue.
