Table 2.
Reported use of medical therapies for feline biliary disease
| Disease | Therapy |
|---|---|
| NC 27 | Metronidazole 30 mg/kg q24h PO and amoxicillin 10 mg/kg q12h PO for 2 months |
| NC26,28 | Amoxicillin/clavulanate 45 mg q12h SC initially, then 50 mg PO q12h for 4 weeks in total (cat body weight 2.85 kg), or ticarcillin/clavulanate PO for at least 4 weeks |
| NC 26 | UDCA 50 mg q24h PO and vitamin K1 6 mg q24h PO |
| NC and cholecystitis 26 | Enrofloxacin 2.5 mg/kg q12h SC |
| NC and cholecystitis 26 | Amoxicillin/clavulanate 100 mg q8h IV, ciprofloxacin 30 mg q24h PO and UDCA 30 mg q24h PO (cat body weight 2.3 kg) for 2 weeks |
| NC and cholecystitis 26 | Amoxicillin 70 mg q12h SC |
| NC and cholecystitis 26 | Doxycycline 50 mg q12h PO and cephalexin IV for 7 days, then 112.5 mg q12h PO for 4 weeks in total |
| Cholecystitis 52 | NSAIDs |
| Cholecystitis7,35 | Chloramphenicol Fluoroquinolones Amoxicillin/clavulanate Metronidazole |
| Gallbladder rupture, NC and cholecystitis 26 | Cefoxitin 120 mg q8h IM and amoxicillin 100 mg q12h PO |
| Choledochal cyst 30 | Pre-surgery (and continued for 3 days): amoxicillin/clavulanate 60 mg q8h IV and metronidazole 30 mg q12h IV Post-surgery: amoxicillin/clavulanate 50 mg q12h PO, metronidazole 33.3 mg q12h PO, UDCA 37.5 mg q24h PO, S-adenosylmethionine 50 mg q24h PO, vitamin E 10 mg q24h PO and vitamin K 0.05 mg q24h PO |
| EHBDO 24 | 4 week course of potentiated amoxicillin 15 mg/kg q12h PO, metronidazole 15 mg/kg q24h PO, and Samylin* 1 g sachet q24h PO |
| LC 53 | Prednisolone 1–2 mg/kg q24h PO for 4–6 weeks, followed by gradual dose tapering |
| LC,53 mucocele, choleliths, cholestasis18,39 | UDCA 15 mg/kg q24h PO |
| LC 29 | Prednisolone (up to 4 mg/kg PO) for an initial period of 3 weeks, followed by gradual dose tapering over 6–8 weeks |
| EHBDO 32 | Amoxicillin/clavulanate 20 mg/kg q8h IV, metronidazole 10 mg/kg q12h IV, buprenorphine 30 mg/kg q8h IM, and vitamin K1 0.5 mg/kg q12h SC (for 3 days); followed by cephalexin 15 mg/kg q12h PO, metronidazole 10 mg/kg q12h PO and UDCA 10 mg/kg PO q24h (antibiotics for a total duration of 4 weeks) |
| Lipidosis 39 | Metaclopramide 0.05 mg/kg/h IV and ranitidine 1.5 mg/kg q12h IV |
| Hepatic encephalopathy 39 | Lactulose 1 ml q8h PO |
*
S-adenosyl L-methionine/silybin/vitamin E liver supplement (VetPlus)
NC = neutrophilic cholangitis; UDCA = ursodeoxycholic acid; EHBDO = extrahepatic bile duct obstruction; LC = lymphocytic cholangitis; NSAIDs = non-steroidal anti-inflammatory drugs; PO = orally; IV = intravenously; SC = subcutaneously; IM = intramuscularly