Table 1.

Semiquantitative evaluation of toxic changes in the cytoplasm of neutrophils

Neutrophils with toxic change
Few	5–10%
Moderate	11–30%
Many	>30%
Severity of toxic change in cytoplasm
Döhle bodies*	1+
Mildly basophilic	1+
Moderately basophilic with Döhle bodies	2+
Moderately basophilic and foamy	2+
Dark blue–gray and foamy†	3+
Basophilic with toxic granules† (not reported in cats)	3+

^*One or two Döhle bodies are sometimes seen in a few neutrophils from cats that do not exhibit signs of illness

^†May also contain Döhle bodies

From Harvey (2012), ¹ with permission