Table 1.

List of various major and minor adipokines secreted by adipose and other tissues.

Adipokine	Selected Sites of Synthesis
Leptin	Adipocytes, cardiomyocyte, vascular endothelial cells
Adiponectin	Adipocytes, skeletal muscle, cardiomyocytes
Apelin	Adipocytes, cardiomyocyte, pancreas, stomach
Chemerin	Adipocytes, liver, lung, placenta
Resistin	Adipocytes, blood monocytes, liver
Visfatin	Adipocytes, lymphocytes, macrophages
Omentin	Adipocytes (primarily visceral)
Vaspin	Adipocytes, hypothalamus, stomach, liver, pancreas
Progranulin	Adipocytes, CNS
Interleukin-6	Adipocytes, t cells, macrophages, fibroblasts
MCP-1	Adipocytes, macrophages, epithelial cells, endothelial cells
PAI-1	Adipocytes, vascular endothelium, macrophages, cardiomyocyte
RBP-4	Adipocytes, macrophages, liver
TNFα	Adipocytes, macrophages, endothelial cells, cardiomyocytes
CTRP-4	Adipocytes, brain, skeletal muscle

Table summarizes adipokines thus far identified and summarizes selected sites of synthesis although numerous additional sources for individual adipokines have been reported. CNS is the central nervous system; MCP-1 is monocyte chemotactic protein-1; PAI-1 is plasminogen activator inhibitor-1; RBP-4 is retinol binding protein-4; TNFα is tumor necrosis factor-alpha; CTRP-4 is C1q/TNF-related protein-4.