Table 3.
Top 16 compounds with key biomarker interactions.
| Id | Label | Degree | Betweenness | Gene |
|---|---|---|---|---|
| D014635 | Valproic Acid | 3 | 602.42 | PTPN11/IRAK3/ANXA2 |
| C012589 | trichostatin A | 2 | 353.98 | IRAK3/ANXA2 |
| D015655 | 1-Methyl-4-phenylpyridinium | 2 | 178.47 | IRAK3/ANXA2 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | 2 | 178.47 | IRAK3/ANXA2 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | 2 | 178.47 | IRAK3/ANXA2 |
| C006632 | arsenic trioxide | 2 | 178.47 | IRAK3/ANXA2 |
| D019327 | Copper Sulfate | 2 | 178.47 | IRAK3/ANXA2 |
| D016572 | Cyclosporine | 2 | 178.47 | IRAK3/ANXA2 |
| D004791 | Enzyme Inhibitors | 2 | 178.47 | IRAK3/ANXA2 |
| C059514 | resveratrol | 2 | 178.47 | IRAK3/ANXA2 |
| D012822 | Silicon Dioxide | 2 | 178.47 | IRAK3/ANXA2 |
| D014750 | Vincristine | 2 | 178.47 | IRAK3/ANXA2 |
| D000082 | Acetaminophen | 2 | 69.97 | PTPN11/ANXA2 |
| D005557 | Formaldehyde | 2 | 69.97 | PTPN11/ANXA2 |
| D008741 | Methyl Methanesulfonate | 2 | 69.97 | PTPN11/ANXA2 |
| C017947 | sodium arsenite | 2 | 69.97 | PTPN11/ANXA2 |