Table 3. Antimicrobial susceptibility of Klebsiella pneumoniae isolates.
| Antimicrobial | Interpretative Resistance MIC Breakpoint, (mcg/mL) | MIC (mcg/mL) | Resistant Isolates, N | (%) | ||
|---|---|---|---|---|---|---|
| Minimum | Maximum | Median (p50) | ||||
| Amikacin | ≥ 64 | < 8 | ≥ 32 | < 8 | 16 | (24.6) |
| Gentamicin | ≥ 16 | < 2 | ≥ 8 | ≥ 8 | 49 | (75.3) |
| Ciprofloxacin | ≥ 4 | 2 | ≥ 2 | ≥ 2 | 65 | (100) |
| Cefepime | ≥ 16 | 16 | ≥ 16 | ≥ 16 | 65 | (100) |
| Imipenem | ≥ 4 | 0.25 | ≥ 32 | ≥ 8 | 60 | (92.3) |
| Meropenem | ≥ 4 | 0.25 | ≥ 32 | ≥ 8 | 62 | (95.4) |
| Polymyxin B | > 2 | 0.125 | 64 | > 2 | 34 | (52.3) |
| Tigecyclinea | > 1 | 0.5 | > 4 | 1 | 9 | (33) |
Antimicrobial susceptibility of 65 carbapenem-resistant Klebsiella pneumoniae bloodstream isolates. Notes: MIC–Minimum inhibitory concentration; p50 – 50th percentile of isolates
aSusceptibility tests for tigecycline were performed upon request and subject to drug availability. A total of 27 isolates were tested, with resistance observed in 9 (33%) of them.