Figure 1.
Phenotype and sequence confirmation of TRP1 and LIP2 disruption strains. (A) Verification of TRP1 disruption strains. Transformants that failed to grow on YNBD were trp− mutants. A representative sample is shown for the alignments of the TRP1 gene sequence from selected trp− mutants. (B) Verification of LIP2 disruption strains. Transformants that exhibited a reduced halo of triglyceride hydrolysis on YNBD-triglyceride were lip− mutans. A representative sample is shown for the alignments of the LIP2 gene sequence from selected lip− mutants. The blue represents gRNA sequence, the red represents indels, and the sequence in green rectangle represents PAM sequence.
