Figure 6.

Experimental procedure of the model of DNCB-induced atopic dermatitis. The mice in the Normal group were treated with 9:1 PBS/olive oil. AD was induced by DNCB in BALB/c mice. Following initial sensitization with 1% DNCB, the BALB/c mice were dorsally treated with 0.5% DNCB 3 times a week for 3 weeks. CP and terfenadine preparations of 1 and 0.1 mg in 200 µL of PBS/olive oil (9:1) were applied on the dorsal skin of the mice in the CP and terfenadine groups every day for 21 days. Normal, untreated group; DNCB, DNCB-sensitized group; CP, CP 1 mg treated group; Terfenadine, Terfenadine 0.1 mg treated group.