Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 7;22(1):37. doi: 10.3390/md22010037

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The bottom-up biomimetic approach (biology-push process) inspired by MCT according to the model proposed by Trotter et al. [16] (arrangement freely inspired by [77]). (a) The biological model: sea-cucumber dermis. (b) The basic structural (A) and functional (B) features of the mutability phenomenon (B: redrawn and modified from [72]). (c) Natural MCT model and its main components: the functional principle is based on dynamic interactions between collagen fibrils and ECM proteoglycans and glycoproteins (see Figure 2 of this review). (d) Basic scheme of a simple MCT-inspired biomimetic model as proposed by Trotter, consisting of a synthetic fibrous composite with dynamic interactions between the components. In the stiff condition, crosslinks are formed by the interaction of catechol and phenylboronic acid. In the soft condition, crosslinks are reversed by the oxidation of catechol to orthoquinone (modified from Trotter, unpublished). (e) Technical applications of this operating principle in a fibrous nanocomposite with dynamically controlled stiffness (redrawn and modified from [17]). (1–6) Employment perspectives of MCT-inspired models.