Figure 4.

Transmission electron microscopy image of two neighbouring platelets (Plt₁ and Plt₂). Plt₁ is in close proximity to a just-shedded multivesicular cargo (MVC)—a complex group of platelet-derived membrane-bound structures that activate and regulate intercellular pathways. MVC are vectors of transport for nucleic acids, proteins, and lipids, regulating the local microenvironment (but also remotely) with implications in cellular functions’ modulation or tissue regeneration/repair. gly—glycogen; m—mitochondria; OCS—open canalicular system. (Courtesy of Dr. E.T. Fertig, “Victor Babeş” National Institute of Pathology, Bucharest, Romania).