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. 2023 Dec 25;14(1):40. doi: 10.3390/life14010040

Table 1.

Classification proposed by Dohan Ehrenfest et al. for platelet concentrates based on their cell content and fibrin architecture [249,250].

Category Name Description
I Pure PRP (P-PRP) Leukocyte-poor preparations with a low-density fibrin network upon activation.
II Leukocyte and platelet-rich plasma (L-PRP) Contains leukocytes and forms a low-density fibrin network upon activation.
III Pure platelet-rich fibrin (P-PRF) Leukocyte-poor preparations with a high-density fibrin network. Mixed with an activator and requiring a specific separator gel.
IV Leukocyte and PRF (L-PRF) Contains leukocytes and has a high-density fibrin network. Blood is centrifuged immediately after collection without the use of anticoagulants, thrombin, or CaCl2.