Table 3.
Hemoglobin level and C.E.R.A. dose (absolute and normalized to body weight or body surface area) at first and last observation on treatment, stratified by route of administration
| PD subcutaneous |
PD intravenous |
PD all routes |
HD | |||||
|---|---|---|---|---|---|---|---|---|
| First obs n = 75 |
Last obs n = 73 |
First obs n = 46 |
Last obs n = 53 |
First obs n = 177 |
Last obs n = 177 |
First obs n = 52 |
Last obs n = 52 |
|
| Hemoglobin, g/dL | 11.2 (2.0) | 10.9 (1.8) | 10.8 (1.8) | 11.2 (1.4) | 11.0 (1.9) | 10.9 (1.7) | 10.2 (1.6) | 10.4 (1.7) |
| C.E.R.A. monthly dose, µg | 100 (50–161) | 100 (50–161) | 100 (50–120) | 100 (50–120) | 100 (50–120) | 100 (50–150) | 107 (80–129) | 80 (54–129) |
| C.E.R.A. monthly dose, µg/kg | 3.5 (2.6–5.4) | 3.6 (2.5–5.1) | 3.5 (2.3–5.3) | 3.0 (1.9–4.7) | 3.4 (2.3–5.4) | 3.5 (2.3–5.1) | 2.9 (1.7–4.0) | 2.1 (1.2–3.4) |
| C.E.R.A. monthly dose, µg/m2 | 96 (73–131) | 101 (69–141) | 95 (60–139) | 89 (54–118) | 94 (67–144) | 95 (62–145) | 89 (59–115) | 63 (40–98) |
Hemoglobin is given as mean (SD), doses as median (interquartile range). The results of three patients on HD treated subcutaneously are not shown
C.E.R.A. continuous erythropoietin receptor activator, HD hemodialysis, obs observations, PD peritoneal dialysis, SD standard deviation