Table 4.
HLA-DRB1*0101-restricted CD4+ T cell epitopes identified in the literature (May 2021)
| Protein | Start | End | Length | Sequence |
|---|---|---|---|---|
| Spike | 530 | 544 | 15 | STDLIKNQCVNFNFN |
| Envelope | 26 | 40 | 15 | FLLVTLAILTALRLC |
| Membrane | 36 | 50 | 15 | QFAYANRNRFLYIIK |
| 66 | 80 | 15 | VLAAVYRINWITGGI | |
| 71 | 85 | 15 | YRINWITGGIAIAMA | |
| 86 | 100 | 15 | CLVGLMWLSYFIASF | |
| 91 | 105 | 15 | MWLSYFIASFRLFAR | |
| 116 | 130 | 15 | TNILLNVPLHGTILT | |
| 136 | 150 | 15 | SELVIGAVILRGHLR | |
| 146 | 160 | 15 | RGHLRIAGHHLGRCD | |
| 151 | 165 | 15 | IAGHHLGRCDIKDLP | |
| 161 | 175 | 15 | IKDLPKEITVATSRT | |
| 166 | 180 | 15 | KEITVATSRTLSYYK | |
| 176 | 190 | 15 | LSYYKLGASQRVAGD | |
| 191 | 205 | 15 | SGFAAYSRYRIGNYK | |
| Nucleoprotein | 81 | 95 | 15 | DDQIGYYRRATRRIR |
| 86 | 100 | 15 | YYRRATRRIRGGDGK | |
| 126 | 140 | 15 | NKDGIIWVATEGALN | |
| 211 | 225 | 15 | AGNGGDAALALLLLD | |
| 216 | 230 | 15 | DAALALLLLDRLNQL | |
| 221 | 235 | 15 | LLLLDRLNQLESKMS | |
| 261 | 275 | 15 | KRTATKAYNVTQAFG | |
| 301 | 315 | 15 | WPQIAQFAPSASAFF | |
| 317 | 331 | 15 | MSRIGMEVTPSGTWL | |
| 326 | 340 | 15 | PSGTWLTYTGAIKLD | |
| 346 | 360 | 15 | FKDQVILLNKHIDAY | |
| 351 | 365 | 15 | ILLNKHIDAYKTFPP | |
| ORF1ab | 5041 | 5055 | 15 | SHRFYRLANECAQVL |
| 5246 | 5260 | 15 | LMIERFVSLAIDAYP | |
| ORF3a | 106 | 120 | 15 | LYLYALVYFLQSINF |
| 116 | 130 | 15 | QSINFVRIIMRLWLC | |
| ORF8 | 36 | 50 | 15 | PCPIHFYSKWYIRVG |
| 41 | 55 | 15 | FYSKWYIRVGARKSA | |
| 76 | 90 | 15 | IGNYTVSCLPFTINC | |
| 86 | 100 | 15 | FTINCQEPKLGSLVV | |
| 96 | 110 | 15 | GSLVVRCSFYEDFLE | |
| 101 | 115 | 15 | RCSFYEDFLEYHDVR |