Table 2.

Candidate genes under positive selection signatures in hot-arid conditions.

Sweep regions	Candidate genes and functions
Chr1: 17600000–17680000	TAFA5: role in cytokine activity22
Chr1: 56420000–56440000	TRIM24: involved in cytokine pathways and the inflammatory response32,33
Chr1: 59080000–59110000	BICD1: participates in the development and function of the nervous system34
Chr2: 28560000–28580000	TSPAN13: involved in the regulation of calcium ion transmembrane transport22 AGR2: involved in the inflammatory response22
Chr2: 47230000–47260000	DPY19L1: role in neuronal migration in the developing mouse cerebral cortex35
Chr3: 30900000–30920000	MRPS18A: cortical bone formation36
Chr5: 15250000–15290000	CHID1: involved in negative regulation of cytokine production; inflammatory response22
Chr5: 15320000–15380000	MUC6: involved in the maintenance of gastrointestinal epithelium; intestinal barrier function in chicken22,37
Chr5: 29080000–29100000	ARG2: anti-inflammation associated38
Chr7: 27830000–27850000	KALRN: key regulatory role in abdominal fat deposition39
Chr7: 32950000–32980000	ARHGAP15: involved in signal transduction22
Chr8: 27480000–27510000	NFIA: necessary for articular cartilage differentiation40
Chr11: 11440000–11460000	CMTM3: involved in positive regulation of B cell receptor signalling pathway22,41 CKLF: this may play an important role in the inflammation and regeneration of skeletal muscle42 TK2: kinase activity22
Chr19: 710000–730000	SUPT4H1: viral infection pathway43