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. 2024 Jan 16;34(1):41–53. doi: 10.1089/thy.2023.0337

Table 5.

Test Performance: Diagnostic Accuracy Parameters of Molecular Diagnostics and [18F]FDG-PET/CT in Oncocytic Nodules (n = 29)

A priori ROM 28%
MD
[18F]FDG-PET/CT
p
Histopathology
Test result Malignant or borderline Benign Malignant or borderline Benign
Positive 7 11 8 20  
Negative 1 10 0 1  
MD on cytology (n = 29), assuming nodules under active surveillance are benign, % [CI]
 Sensitivity 88 [47–100] 100 [63–100] n.a.a
 Specificity 48 [26–70] 5 [0–24] 0.004
 PPV 39 [17–64] 29 [13–49]  
 NPV 91 [59–100] 100 [3–100]  
 BCR 38 [21–58] 3 [0–18]  
a

Not able to calculate McNemar test.

n.a., not applicable.