Table 5.
Test Performance: Diagnostic Accuracy Parameters of Molecular Diagnostics and [18F]FDG-PET/CT in Oncocytic Nodules (n = 29)
|
A priori ROM 28% |
MD |
[18F]FDG-PET/CT |
p | ||
|---|---|---|---|---|---|
| Histopathology | |||||
| Test result | Malignant or borderline | Benign | Malignant or borderline | Benign | |
| Positive | 7 | 11 | 8 | 20 | |
| Negative | 1 | 10 | 0 | 1 | |
| MD on cytology (n = 29), assuming nodules under active surveillance are benign, % [CI] | |||||
| Sensitivity | 88 [47–100] | 100 [63–100] | n.a.a | ||
| Specificity | 48 [26–70] | 5 [0–24] | 0.004 | ||
| PPV | 39 [17–64] | 29 [13–49] | |||
| NPV | 91 [59–100] | 100 [3–100] | |||
| BCR | 38 [21–58] | 3 [0–18] | |||
Not able to calculate McNemar test.
n.a., not applicable.