FIG. 1.

Bacterial numbers in spleens of BALB/c mice 7 days p.i. with 2 × 10³ Y. enterocolitica and administration of PBS containing control Abs or anti-CD4 Abs 1 day prior to infection. On day +3 p.i., mice were treated with PBS containing control or anti-CD4 Abs without or in combination with anti-CD8, anti-asialo GM1 (NK), or anti-CD8 plus anti-asialo GM1 Abs. Results are the means and standard deviations for four mice. The asterisks indicate statistically significant differences (P < 0.01) compared with the values obtained with the control group (∗ for group of mice treated with anti-CD4 MAb alone; ∗∗ for group of mice treated with anti-CD4 MAb plus IL-12). w/o IL-12, without IL-12.