Figure 17.
Biopsy and histology analysis of animal models. (a) Tumor size in HGC-27 and AGS tumor-bearing nude mouse models treated with Res, MSN-SH, or Res-loaded MSNs; (b) inflammatory cell infiltration (H&E staining). Magnification; (c) Ki67 immunohistochemical staining of HGC-27 and AGS cells in tumor-bearing nude mice; (d) apoptosis of HGC-27 and AGS cells treated with Res, MSH-SH, or Res-loaded MSNs, detected by TUNEL. **, p < 0.01, Res group vs. MSN-SH or Control group; ##, p < 0.01, MSN/Res group vs. Res group. Reprinted from Ref. [211]. This work is licensed under the Attribution-NonCommercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0).