Table 4.
Density, flowability, and in vitro aerodynamic characteristics of spray-dried samples.
| Sample Name | F0 | F0.5 | F1 | F2 |
|---|---|---|---|---|
| Bulk Density (g/cm3) | 0.124 ± 0.012 | 0.123 ± 0.003 | 0.120 ± 0.031 | 0.139 ± 0.024 |
| Tapped Density (g/cm3) | 0.180 ± 0.002 | 0.192 ± 0.011 | 0.201 ± 0.009 | 0.228 ± 0.052 |
| Carr’s Index | 31.03 | 35.14 | 40.01 | 39.01 |
| Hausner Ratio | 1.450 | 1.542 | 1.670 | 1.64 |
| MMAD (µm) | 2.40 ± 0.17 | 2.80 ± 0.06 | 4.51 ± 0.41 | 4.90 ± 0.16 |
| FPF (%) | 56.16 ± 2.51 | 71.02 ± 1.19 | 64.32 ± 1.34 | 32.21 ± 3.67 |
| EF (%) | 97.06 ± 3.22 | 96.60 ± 1.65 | 94.82 ± 2.79 | 95.70 ± 2.89 |
MMAD: mass median aerodynamic diameter, FPF: fine particle fraction, EF: emitted fraction. Results are expressed as mean ± SD (n = 3 independent measurements).