Skip to main content
. 2024 Jan 18;16(2):297. doi: 10.3390/nu16020297

Table 1.

Data from animal models of food allergies.

Food Study Probiotic Findings
Cow’s milk Jiang et al.
[36]
L. plantarum HM-22 Increased serum levels of IL-10, IFN-γ, and TGF-β;
Reduced serum levels of total IgE and IL-4;
Reduced gut permeability (increased expression of occludin and claudin-1 in the colon).
Ni et al.
Li et al.
[37,38]
L. acidophilus KLDS 1.0738 Suppression of the TLR4/NF-kB signaling pathway
Fu et al.
[39]
L. plantarum ZDY2013 and L. rhamnosus GG (LGG) Reduced serum levels of total IgE;
Promoted Th1 differentiation, inhibiting Th2 responses;
Improved gut barrier function.
Egg Santos et al.
[40]
B. longum 51A Reduced serum levels of total IgE, gut permeability, proximal jejunal damage, eosinophil and neutrophil recruitment, and levels of eotaxin-1, CXCL1/KC, IL-4, IL-5, IL-6, IL-13, and TNF;
Increased serum levels of IL-10.
Miranda et al.
[41]
A. muciniphila BAA-835
Parrish et al.
[42]
A. muciniphila The presence of A. muciniphila in the microbiota, combined with fiber deprivation, led to stronger anti-commensal IgE coating and innate type 2 immune responses. This worsened food allergy symptoms in animal models of OVA and peanut allergy.
Duan et al.
[43]
L. plantarum JC7 Reduced plasma histamine levels, OVA-specific IgE serum levels, shift in Th1/Th2 immune response, and Treg/Th17 imbalance.
Miranda et al.
[44]
Saccharomyces cerevisiae UFMG A-905 Reduced tissue damage, myeloperoxidase activity levels, and IL-17 serum levels.
Shellfish Fu et al.
[45]
Bacillus coagulans 09.712 Improved gut barrier function;
Suppression of the pro-inflammatory Th17 response.
Fu et al.
[46]
L. casei Zhang Attenuated allergy symptoms and gut epithelial damage;
Favoring a tolerogenic pattern through the activation of the NF-κB signaling pathway.
Fu et al.
[47]
B. infantis Attenuated allergy symptoms;
Induction of Tregs.