ApoE	Apolipoprotein E
AFM	Atomic force microscopy
ASSET	Anchored Secondary scFv Enabling Targeting
CMC	Critical micelle concentration
CFU	Colony forming unit
CRISPR/Cas 9	Clustered regularly interspaced palindromic repeats
CTLA-4	Cytotoxic T-lymphocyte-associated antigen 4
DLS	Dynamic light scattering
DNA	Deoxy nucleic acid
DSC	Differential scanning calorimetry
EA	Edge activators
EE	Entrapment efficiency
FNC	Flash nanocomplexation
GALA	Glutamic acid-alanine-leucine-alanine
HPLC	High-performance liquid chromatography
HPH	High pressure homogenization
LDL	Low-density lipoprotein
LNPs	Lipid nanoparticles
LUVs	Large unilamellar vesicles
LPHNs	Lipid polymer hybrid nanoparticles
mRNA	messenger Ribonucleic acid
MIVM	Multi-inlet vortex mixer
mPES	modified polyethersulphone
MLVs	Multilamellar vesicles
mAbs	monoclonal antibodies
NLC	Nanostructured lipid carriers
PD-1	Programmed cell death protein 1
PD-L1	Programmed cell death ligand 1
PEG	Polyethylene glycol
PES	Polyethersulfone
PP	Polypropylene
PDI	Polydispersity index
PES	Polyethersulfone
PP	Polypropylene
PDI	Polydispersity index
PCS	Photo correlation spectroscopy
PBS	Phosphate buffer saline
PLK1	Polo like kinase
RNA	Ribonucleic acid
R8	Octaarginine (R8) cell-penetrating peptide
SNALP	Stable nucleic acid lipid nanoparticle
siRNA	small interfering Ribonucleic acid
SLN	Solid lipid nanoparticles
SCF	Supercritical fluid technology
scCO2	Supercritical carbon dioxide
SEM	Scanning electron microscope
TFF	Tangential flow filtration
TEM	Transmission electron microscope
USFDA	United States Food and Drug Administration
XRD	X-ray diffraction
ZP	Zeta potential