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. 2024 Jan 13;16(1):107. doi: 10.3390/pharmaceutics16010107

Table 5.

EC50 of 50 and 200 nm INI-4001/A-SNP formulations from mBMDCs. A summary of 2–4 independent assays is presented. EC50 (µM) was calculated by Prism 8. * Denotes p < 0.05 by Student’s t test versus INI-4001/A-SNP high.

50 nm INI-4001/A-SNP 200 nm INI-4001/A-SNP
Cytokine Low High Low High Aqueous INI-4001
IL-6 40 ± 10 * 133 ± 23 20 ± 2 * 72 ± 15 19 ± 3
TNF-α 49 ± 15 * 117 ± 13 35 ± 5 95 ± 25 48 ± 12
IL-12 62 ± 31 * 58 ± 20 22 ± 3 52 ± 27 <1