Table 3.

Main EDCs implicated in hepatic injury.

EDCs	Name	Molecular Targets	Study Model
Solvents/lubricants	Bisphenyl polychlorinates (PCBs)	Corticosterone levels, liver fibrosis	Mice, male [30]
	Bisphenyl polybrominated (PBBs)	Fecundit cells, liver steatosis	Mice [31]
	Per- and polyfluoroalkyl substances (PFOS)	Liver injury, PFASs	mice [32]
	Dioxins	Cell-mediated immunity, liver injury	Human, mice [33]
Plasticizers	Bisphenol A (BPA)	Fertility, liver steatosis	Mice, male female [34]
	Phthalates	Insulin resistance and type II diabetes, overweight and obesity, liver steatosis	Male, female and children [35]
	Di(2-ethylhexyl) phthalate (DEHP)	Liver injury	Mice [36]
Pesticides	Cypermethrin (CYP), atrazine (ATZ)	liver injury, growth parameters	Mice [37]
	Dichlorophenyltrichloroethane (DDT)	neonatal body weight, liver damage	Mice, male, children [38]
	Permethrin	Dopamine transport, fatty liver	Mice, human [39]
Drugs	Diethylstilbestrol (DES)	Expression of PDGF receptor, neonatal body weight, fatty liver	male and female/mice [40]
Heavy Metals	Arsenic	apoptotic index, liver injury	Mice [41,42]
	Cadmium	Expression of metallothionein, pS2/TFF1, liver steatosis	Mice [43,44,45]
	Mercury	Growth, hepatic steatosis	Mice, human [44]