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. 2024 Jan 20;16(2):309. doi: 10.3390/nu16020309

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Maternal fructose intake affects placental cysteine bioavailability of their descendants. Placental levels of specific mRNA for (A) SLC6A6, (B) CSAD, and (C) Cys-Dio. Placental (mRNA) expression from control mothers (CC, empty bar), or pregnant rats from fructose-fed mothers subjected (FF, black bar) or not (FC, grey bar) to fructose intake throughout pregnancy. Data are expressed as means ± S.E., n = 5 (CC); 4 (FC); and 5 (FF) rats. Values not sharing a common letter are significantly different (p < 0.05). Relative target gene mRNA levels were measured by real-time PCR as explained in Materials and Methods, normalized to Rps29 levels and expressed in arbitrary units (a.u.). SLC6A6: solute carrier family 6 member 6; CSAD: cysteine sulfinic acid decarboxylase; Cys-Dio: cysteine dioxygenase.