API	active pharmaceutical ingredient
ASO	antisense oligonucleotide
AUC	area under the curve
BA	bioavailability
C8	caprylic acid, octanoic acid
C10	capric acid, decanoic acid
COG	cost of goods
cEt	constrained ethyl
CPPs	cell-penetrating peptides
cLogD	calculated octanol-water distribution coefficient
cLogP	calculated octanol-water partition coefficient
EDTA	ethylenediaminetetraacetic acid
EPSA	experimental polar surface area
FDA	United States Food and Drug Administration
GalNAc	N-acetylgalactosamine
GRAS	generally recognized as safe
HBAs	number of hydrogen bond acceptors
HBDs	number of hydrogen bond donors
IJ	intrajejunal
IV	intravenous
MW	molecular weight
MPSA	molecular (3D) polar surface area in nonpolar environment
Ms	microsomes
NAr	number of aromatic rings
NMR	nuclear magnetic resonance
LD50	median lethal dose
LPE	lipophilic permeability efficiency
NF-kB	nuclear factor kappa B
NOAEL	no-observed-adverse-effect level
P450	cytochrome P450
P-gp	P-glycoprotein
PO	per oral
TPSA	topological polar surface area
SC	subcutaneous
siRNA	small interfering RNA
SNAC	salcaprozate sodium
TEER	transepithelial electrical resistance
TNF-α	tumor necrosis factor α
TPDs	target protein degraders