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. 2024 Jan 12;14(1):114. doi: 10.3390/life14010114

Table 2.

The characteristics of the study population.

Variables * All Patients Mild Disease (n = 180) Moderate
Disease (n = 143)
Severe Disease (n = 43) p-Value
Age 54.48 ± 16.48 53.86 ± 17.46 57.51 ± 12.89 54.35 ± 16.18 0.43
Gender
  Male 219 101 (56%) 91 (64%) 27 (63%) 0.36
  Female 147 79 (44%) 52 (36%) 16 (37%)
WBC 7.49 [7.15–7.83] 6.77 [6.38–7.26] 8.08 [7.60–8.73] 7.98 [7.50–8.42] <0.001
Platelets 238.25
[230.93–243.69]
231.70
[220-.95–240.22]
243.20
[221.87–265.52]
245
[236.51–259.56]
0.11
Neutrophils 4.42 [4.22–4.69] 3.80 [3.44–4.25] 4.68 [4.39–5.26] 4.96 [4.57–5.45] <0.001
Lymphocytes 2.10 [1.97–2.23] 2.22 [1.99–2.30] 2.16 [1.91–2.34] 1.97 [1.79–2.20] 0.12
Monocytes 0.51 [0.48–0.53] 0.49 [0.45–0.52] 0.52 [0.47–0.56] 0.53 [0.48–0.57] 0.59
PLR 114.96
[110.45–121.10]
108.07
[100.89–115.10]
110.75
[96.66–126.26]
129.79
[117.02–135.15]
0.002
NLR 2.05 [1.90–2.19] 1.73 [1.59–1.88] 2.23 [1.93–2.66] 2.53 [2.20–2.79] <0.001
d-NLR 1.55 [1.44–1.65] 1.37 [1.29–1.49] 1.45 [1.36–1.82] 1.80 [1.62–1.95] 0.001
MLR 0.23 [0.22–0.25] 0.22 [0.21–0.25] 0.25 [0.23–0.28] 0.24 [0.22–0.26] 0.04
PMR 475.02
[450.39–508.40]
479.08
[440.36–526.90]
467.59
[400–539.75]
476.42
[437.62–524.45]
0.75
SII 478.52
[453.65–521.85]
404.61
[357.44–446.03]
541.21
[464.89–602.06]
560.46
[518.95–646.30]
<0.001
SIRI 1.03 [0.93–1.09] 0.86 [0.79–0.92] 1.23 [1.01–1.44] 1.27 [1.07–1.37] 0.001
AISI 255.83
[229–273.18]
196.96
[168.52–221.22]
287.76
[258.18–331.08]
293.10
[272.01–335.63]
0.001
ESR 15
[12.8–17]
12.80
[11.80–15.80]
16.20
[12.20–20.98]
18
[14–20]
0.17

WBC, white blood cell count; PLR, platelet-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio; d-NLR, derived neutrophil-to-lymphocyte ratio; MLR, monocyte-to-lymphocyte ratio; PMR, platelet-to-monocyte ratio; SII, systemic immune inflammation index; SIRI, systemic inflammation response index; AISI, aggregate index of systemic inflammation; ESR, erythrocyte sedimentation rate; * refer to Table 1 for measurement units.