AD	Alzheimer’s disease
CNS	Central nervous system
BBB	Blood–brain barrier
APOE	Apolipoprotein E
PSEN	Presenilin
APP	Amyloid precursor protein
NMDA	N-methyl-D-aspartate receptor
NFT	Neurofibrillary tangles
CS-NP	Chitosan nanoparticles
ChAT	Choline acetyltransferase
PIP	Piperine
PAMAM	Poly (amidoamine)
PVA	Polyvinyl alcohol
PLGA	poly lactic co glycolic acid
HPMC	Hydroxypropyl methylcellulose
i.n	Intranasal
i.v	Intravenous
NP	Nanoparticles
SLN	Solid lipid nanoparticles
NLC	Nanostructured lipid carrier
Lf-TMC-NP	Lactoferrin conjugated N-methylated chitosan nanoparticles
RSLN	Risperidone solid lipid nanoparticles
PDI	Polydispersibility Index
EE	Entrapment efficiency
BuChE	Butyrylcholinesterases
AChEI	Acetylcholinesterase inhibitor
ROS	Reactive oxygen species
ARIA	Amyloid-related imaging abnormality
FDC	Fixed dose combination
OLE	Open label extension
PET	Photon emission topography
PEG	Polytheylene glycol
AMT	Adsorption mediated transcytosis
Tg	Glass transition temperature
PLGA	Polylactide-co-glycolide
LNP	Lipid nanoparticles
MOF	Metal organic framework
MDA	Malonyldialdehyde
IVIVC	In vitro in vivo correlation
RHT	Rivastigmine
TNF	Tumour necrosis factor
ELISA	Enzyme-linked immunosorbent assay
TRAIL	TNF-related apoptosis-inducing ligand
mi-RNA	Micro ribonucleic acid
PLA	Polylactic acid
AuNP	Gold nanoparticles
SPION	Super paramagnetic iron oxide nanoparticles
HAS	Hydroxy-α-sanshool
GH	Galantamine hydroxide
OVAL	Ovalalbumin
AUC	Area under the curve
SNF	Simulated nasal fluid
ACSF	Artificial cerebrospinal fluid
PBS	Phosphate buffer saline
DPPH	2,2-diphenyl-1-picrylhydrazyl
FRAP	Ferric reducing ability of plasma
NE	Nanoemulsion
GQR	G alpha subunits
DTE	Drug transport efficiency
DTP	Drug targeting potential
MPP	1-Methyl-4-phenylpyridinium
QD	Quantum dots
WGA	Wheat germ agglutinin
ApoE4	Apolipoprotein E4
GQD	Graphene quantum dots
FTIR	Fourier transform infrared spectroscopy
HPLC	High-performance liquid chromatography
Cmax	Maximum concentration
EMA	European Medicines Agency
NBCD	Non-biological complex drugs
IND	Investigational new drug
Aβ42	42-amino acidβ amyloid