Table 3.

Experimental design study relating endometriosis and gluten-free diet.

Authors	Type of Study	Duration of GFD	Population	Methods	Results	Author’s Conclusions
Marziali M. et al., 2012 [83]	Retrospective study	1 year of GFD	207 women with severe painful endometriosis-related symptoms	Baseline values of painful symptoms were assessed by Visual Analogue Scale (VAS) for dysmenorrhea, nonmenstrual pelvic pain, and dyspareunia, and re-evaluated after 12 months	At 12-month follow-up, 156 patients (75%) reported statistically significant change in painful symptoms (p < 0.005), 51 patients (25%) reported any improvement of symptoms. No patients reported worsening of pain. A considerable increase in scores for all domains of physical functioning, general health perception, vitality, social functioning, and mental health was observed in all patients (p < 0.005)	Painful symptoms of endometriosis decrease after 12 months of GFD

GFD: gluten-free diet.