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. 2023 Dec 21;17(1):16. doi: 10.3390/ph17010016

Table 2.

Adverse effects of ketamine.

Adverse Effects of Ketamine
Central nervous system
  • Dizziness [17]

  • Blurred vision [17]

  • Altered hearing [17]

  • Nausea and vomiting [17]

  • Vivid dreams, hallucinations [17]

  • Higher likelihood of depression relapse in patients with repeated intravenous doses [86]

  • Psychotic behavior, schizophrenia-like symptoms [114]

  • Cognitive abnormalities [114]

  • Effects similar to aging processes and Alzheimer’s disease due neuroapoptotic effects of long-term use [120,121,122]

  • Impaired short-term and long-term memory, visual recognition, spatial working memory [125,126,127]

Cardiovascular system
  • Ventricular myocardial apoptosis and fibrosis [134]

  • Cardiac arrhythmia [134]

  • Arterial hypertension [17]

Respiratory system
  • Airway obstruction in pediatric patients, due to laryngospasm because of heightened salivation [132,133]

  • Heightened pulmonary vascular resistance [66,67]

Urinary system,
Digestive system
  • Increase in liver enzymes with repeated use [135,136]

  • Intense abdominal pain [136,137]

  • Dilation of the bile ducts [137]

Eye
  • Bilateral corneal edema [138]