Table 1.
Scenario | Primary Target Population | Secondary Target Populations |
---|---|---|
Base Case: Current WHO recommendations |
Two-dose schedule for girls under 15 years old. All countries introduce by 2028. |
Only currently planned MAC campaigns with two doses each are for girls under 15 years old and gender-neutral vaccination in countries with such existing recommendations (only girls in other countries). |
Scenario A: One-dose schedules |
One-dose schedule for girls under 15 years old. LICs and LMICs adopt the one-dose schedule in 2023, while UMICs and HICs (including China) have a delayed switch in 2025. |
As in base case, except that MAC campaigns for girls under 15 years old will also use one-dose schedule. |
Scenario B: One-dose schedules and gender-neutral vaccination |
As in Scenario A. One-dose schedule for girls under 15 years old. LICs and LMICs adopt the one-dose schedule in 2023, while UMICs and HICs (including China) have a delayed switch in 2025. |
As in Scenario A, but all countries adopt gender-neutral vaccination in the same year as the implementation of the one-dose schedule (unless already implemented). |
Scenario C: Gender-neutral vaccination in HICs and MICs |
As in Base Case. Two-dose schedule for girls under 15 years old. All countries introduce by 2028. |
As in base case and all HICs and UMICs (including China) implement gender-neutral vaccination. Gavi-supported countries introduce with MACs for girls under 15 years old. |
Scenario D: To achieve global cervical cancer elimination goals |
As in base case, but assumes that all countries will achieve at least 90% coverage by 2030. | No MACs or vaccination of boys. |
HIC: high-income country; LIC: low-income country; LMIC: lower-middle-income country; MIC: middle-income country; UMIC: upper-middle-income country.