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. 2023 Dec 19;12(1):4. doi: 10.3390/vaccines12010004

Table 1.

Demand forecasting scenarios.

Scenario Primary Target Population Secondary Target Populations
Base Case:
Current WHO
recommendations
Two-dose schedule for girls under 15 years old.
All countries introduce by 2028.
Only currently planned MAC campaigns with two doses each are for girls under 15 years old and
gender-neutral vaccination in countries with such existing
recommendations (only girls in other countries).
Scenario A:
One-dose schedules
One-dose schedule for girls under 15 years old. LICs and LMICs adopt the one-dose schedule in 2023, while UMICs and HICs
(including China) have a delayed switch in 2025.
As in base case, except that MAC campaigns for girls under 15 years old will also use one-dose schedule.
Scenario B:
One-dose schedules and gender-neutral vaccination
As in Scenario A.
One-dose schedule for girls under 15 years old. LICs and LMICs adopt the one-dose schedule in 2023, while UMICs and HICs
(including China) have a delayed switch in 2025.
As in Scenario A, but all countries adopt gender-neutral
vaccination in the same year as the
implementation of the one-dose schedule (unless already
implemented).
Scenario C:
Gender-neutral
vaccination in HICs and MICs
As in Base Case.
Two-dose schedule for girls under 15 years old.
All countries introduce by 2028.
As in base case and all HICs
and UMICs (including China)
implement gender-neutral
vaccination.
Gavi-supported countries
introduce with MACs for girls under 15 years old.
Scenario D:
To achieve global cervical cancer
elimination goals
As in base case, but assumes that all countries will achieve at least 90% coverage by 2030. No MACs or vaccination of boys.

HIC: high-income country; LIC: low-income country; LMIC: lower-middle-income country; MIC: middle-income country; UMIC: upper-middle-income country.