Table 1.

Nasopharyngeal cancer histology and clinicopathological features.

	WHO I	WHO II	WHO III
Differentiation status	well differentiated	moderately to poorly differentiated	undifferentiated
Histological category in WHO classification	keratinizing	nonkeratinizing-differentiated	nonkeratinizing-undifferentiated
TIL infiltration	fair to moderate	heavy
EBERs in tumor	(−) or faint	(+)
EBV antibodies	not elevated	elevated
Chemoradiosensitivity	moderate	good
Metastatic property	low to moderate	high
Epidemiology	20% in non-endemic area; <5% in endemic areas	80% in non-endemic areas; >95% in endemic areas

EBERs; EBV-encoded small RNAs, TIL; tumor-infiltrating lymphocytes, WHO; World Health Organization.