Table 3.

Causes of dose reduction and treatment suspension at 12 months.

Dose Reduction	n = 11
Gastrointestinal intolerance	7 (13.0)
Diarrhea	7 (13.0)
Nausea/vomiting	1 (1.9)
Abdominal pain	1 (1.9)
Weight loss	1 (1.9)
Allergic reaction	0 (0.0)
Skin ulcer	0 (0.0)
Cough	0 (0.0)
Upper respiratory tract infection	0 (0.0)
Fatigue	0 (0.0)
Liver enzyme derangement	6 (11.1)
Treatment suspension	n = 15
Gastrointestinal intolerance	11 (20.4)
Diarrhea	8 (14.8)
Nausea/vomiting	2 (3.7)
Abdominal pain	1 (1.9)
Weight loss	2 (3.7)
Allergic reaction	0 (0.0)
Skin ulcer	0 (0.0)
Cough	0 (0.0)
Upper respiratory tract infection	0 (0.0)
Fatigue	0 (0.0)

Data are presented as No. (%).