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Vaccination is broadly protective in genetically paired mice post-infection. (A) Differences in percent weight loss at day 4 between paired mice, based on genetic relatedness, vaccinated with either PBS (control) vaccination or S2P + RIBI. (B) Differences in lung viral load measured in pfu/mL between genetic pairs of mice vaccinated with PBS (control) or S2P + RIBI. Pairs were challenged with MA10 at the same time to measure the degree of protection in mice.
