TABLE 3.
Cytokine synthesis induced by bacterial invasion of host cells
| Target cell | Cytokine(s) produced | Invading organism | Reference |
|---|---|---|---|
| Epithelial cells | IL-8 | Salmonella dublin, Y. enterocolitica, Shigella dysenteriae, Listeria monocytogenes | 13 |
| IL-8, MCP-1, GM-CSF, TNF-α | Salmonella dublin, Y. enterocolitica, Shigella dysenteriae, Listeria monocytogenes, enteroinvasive E. coli | 31 | |
| Human umbilical endothelial cells | IL-1β, IL-6 | S. aureus | 63 |
| Human fibroblasts | IFN-β | Shigella flexneri, enteroinvasive E. coli | 26 |
| Macrophages | IL-1β | Shigella flexneri | 64 |