Table 7.
S.No | Author | Year | Country | Number | Parameter used to measure muscle mass | Prevalence | Outcome |
---|---|---|---|---|---|---|---|
1 | Zhang T et al. 93 | 2017 | China |
204 CD‐105 UC‐99 |
L3 skeletal muscle index on CT scan † | 25.5% | Myopenia is associated with higher disease activity and poor clinical outcomes |
2 | Bamba S et al. 94 | 2017 | Japan |
72 CD‐43 UC‐29 |
L3 skeletal muscle index on CT scan † | 42% | Myopenia predicts intestinal resection |
3 | Zhang T et al. 95 | 2017 | China | 114 (CD) | L3 skeletal muscle index on CT scan † | 61.4% | Patients undergoing bowel resection with myopenia had higher post‐operative complications |
4 | Bamba S et al. 96 | 2020 | Japan |
187 CD‐99 UC‐88 |
L3 skeletal muscle index on CT scan † | 34.7% | Myopenia is associated with prolonged hospital stay |
5 | Kang MK et al. 97 | 2020 | South Korea | 443 (UC and CD) | Psoas muscle index on CT ‡ | 34.9% | Sarcopenia was an independent risk factor for NAFLD in patients with IBD |
6 | Kurban M et al. 98 | 2020 | China | 47 (CD) | Bioelectrical impedance analysis | 66% | Body composition analysis is more accurate for muscle mass assessment than nutrition assessment scales |
7 | Lee CH et al. 99 | 2020 | South Korea | 79 (CD) | L3 skeletal muscle index on CT scan † | 51% | Myopenia correlated with CRP levels |
8 | Ge Xi et al. 100 | 2021 | China | 233 (ASUC) | L3 skeletal muscle index on CT scan † | 50.2% | Myopenia associated with failure of response to IV steroid, higher colectomy rates and postoperative complications |
9 | Boparai et al. 101 | 2021 | India | 44 (CD) | L3 skeletal muscle index on CT scan † | 43% | Combination of myopenia and high visceral fat was associated with poor outcomes in CD |
10 | Ge Xi et al. 102 | 2022 | China | 254 (ASUC) | L3 skeletal muscle index on CT scan † | 50% | Sarcopenia is an independent predictor for rescue therapy and colectomy |
11 | Nam K et al. 103 | 2023 | South Korea |
1027 CD‐854 UC‐173 |
L3 skeletal muscle index on CT scan † | 56.8% | Myopenia is associated with perianal CD |
L3 skeletal muscle index: Total cross‐sectional area of the skeletal muscles at L3 level divided by height (in meters) squared.
Psoas muscle index: Total psoas cross‐sectional area at L3 level divided by height (in meters) squared.
ASUC, acute severe ulcerative colitis; CD, Crohn's disease; NAFLD, non‐alcoholic fatty liver disease; UC, ulcerative colitis.